Additional
information

MPX does not spread easily between people. Human-to-human transmission
occurs through contact with:
infectious material from skin lesions
respiratory droplets in prolonged face-to-face contact,
virus-contaminated objects such as bedding or clothing

血液感染について（英国）②

During the 2022 multi-country outbreak, the predominance of cases among
men who have sex with men and the distribution of the MPX skin rash at
presentation, suggests MPX transmission is associated with direct contact
during sex.

Northern Ireland
BLOOD TRANSFUSION SERVICE

followed by scabs. Infectivity may start during initial symptoms and lasts until
the rash clears and all scabs have dropped off.

Contacts may have received Imvanex, a third generation Smallpox vaccination,
to reduce the risk of serious illness. Imvanex is a live attenuated nonreplicating vaccination. For donor selection purposes this should be assessed
as a non-live vaccine. Recipients of Imvanex are eligible to donate once they
satisfy the requirements of the discretionary entry above.
New entry
Northern Ireland
BLOOD TRANSFUSION SERVICE

Reason for Change

Staff should be alert for donors who report rashes and illnesses consistent with
monkeypox, regardless of sexual behaviour, travel history or other risk factors.

Post Donation Illness
followed by scabs. Infectivity may start during initial symptoms and lasts until
the rash clears and all scabs have dropped off.

Donors must be provided with information about contacting the tissue
establishment if they develop any illness within 21 days after donation.
Donation should be discarded

Monkeypox Entry inStaff
the
Living
Tissue
and
Cord
Donor
should
be alert
for donors
who
report Blood
rashes and
illnesses consistent
with
2. Contact
with an individual with Monkeypox
monkeypox, regardless of sexual behaviour, travel history or other risk factors.
Selection Guidelines
1. Affected Individuals
Post Donation Illness
must be provided with information about contacting the tissue
Obligatory:
Must Donors
not donate

Includes

establishment if they develop any illness within 21 days after donation. Obligatory:
be from
discarded
If the Donation
donor has should
recovered
confirmed or suspected Monkeypox (MPX)
Discretionary:
infection and
It is atwith
leastMonkeypox
28 days since the diagnosis of MPX was made, and
2. Contact with an individual
It is at least 14 days since recovery, and the donor remains well, and
It is at least
14 have
days since
skin lesions
have healed,
Includes
Individuals
who
beenall
identified
by public
healthand
teams as a close contact
more than with
seven
days since completing any antiviral or antibiotic
of Itanisindividual
Monkeypox
therapy,
and
Obligatory:
Must
not donate
The donor has been discharged from all follow up (including public
health surveillance)
Discretionary:
If it is more than 21 days since last contact and,
accept

Discretionary:

Additional
Information

the donor has remained well and
theindonor
has completed
isolation
and
MPX is endemic
some African
countries.any
During
2022 aperiod,
multi-country
outbreak was identified
cases
the UK, Europe,
America (including
and other
the donorwith
has
beenindischarged
fromNorth
all follow-up
regions.
surveillance by public health),
accept.

Additional
information

The incubation period of MPX is up to 21 days. The initial symptoms are fever,
myalgia, fatigue and headache. These are followed by a rash starting from the
See additional information below for donors who received vaccination.
site of the primary infection, this rash develops into vesicles and pustules

Individuals who have been identified by public health teams as a close contact
of an individual with Monkeypox
Must not donate
If it is more than 21 days since last contact and,
the donor has remained well and
the donor has completed any isolation period, and
the donor has been discharged from all follow-up (including
surveillance by public health),
accept.
See additional information below for donors who received vaccination.
MPX does not spread easily between people. Human-to-human transmission
occurs through contact with:
infectious material from skin lesions
respiratory droplets in prolonged face-to-face contact,
virus-contaminated objects such as bedding or clothing

Northern Ireland
BLOOD TRANSFUSION SERVICE

Additional
MPX
does not
spread easily between people. Human-to-human transmission
Joint
UKBTS Professional Advisory
Committee
(JPAC)
followed
by scabs.
Infectivity
may
start during initial symptoms and lasts until
JPAC
Office
information
occurs
through
contact
with:
Email: anna.witham@nhsbt.nhs.uk
the rash clears and all scabs have dropped off.

During the 2022 multi-country outbreak, the predominance of cases among
men who have sex with men and the distribution of the MPX skin rash at
presentation, suggests MPX transmission is associated with direct contact
during sex.

infectious material from skin lesions

droplets
prolonged
face-to-face
contact, with
Staff should berespiratory
alert for donors
who in
report
rashes and
illnesses consistent
virus-contaminated
objects such
bedding
or clothing
monkeypox, regardless
of sexual behaviour,
travelas
history
or other
risk factors.
Page 2 of 5

During
theprovided
2022 multi-country
outbreak,
the predominance
Donors
must be
with information
about contacting
the tissue of cases among
men whoif have
sex with
men
andwithin
the distribution
of donation.
the MPX skin rash at
establishment
they develop
any
illness
21 days after
Donation
should be discarded
presentation,
suggests MPX transmission is associated with direct contact
Post Donation
during sex.
information
2. Contact with an individual with Monkeypox
Post Donation Illness

Includes
Obligatory:
Discretionary:

Post Donation
information

Contacts may have received Imvanex, a third generation Smallpox vaccination,

Reason for Change
Individuals
who have
been
by public
health teams
as aattenuated
close contact
to reduce
the risk
of identified
serious illness.
Imvanex
is a live
nonof an individual
MonkeypoxFor donor selection purposes this should be assessed
replicatingwith
vaccination.
Must as
notadonate
non-live vaccine. Recipients of Imvanex are eligible to donate once they

satisfy the requirements of the discretionary entry above.

If it is more than 21 days since last contact and,
the donor has remained well and
If the
donor has retrospectively reported contact with Monkeypox within
the donor has completed any isolation period, and
incubation
donation
could
beall
discarded
seek public health advice to
the donorperiod,
has been
discharged
from
follow-upor
(including

Contacts may have received Imvanex, a third generation Smallpox vaccination,
to reduce the risk of serious illness. Imvanex is a live attenuated nonreplicating vaccination. For donor selection purposes this should be assessed
as a non-live vaccine. Recipients of Imvanex are eligible to donate once they
satisfy the requirements of the discretionary entry above.
If the donor has retrospectively reported contact with Monkeypox within
incubation period, donation could be discarded or seek public health advice to
determine the risk.
New entry

14