よむ、つかう、まなぶ。
資料２－４ 研究報告の報告状況 (4 ページ)
出典
| 公開元URL | https://www.mhlw.go.jp/stf/newpage_24331.html |
| 出典情報 | 薬事・食品衛生審議会 薬事分科会医薬品等安全対策部会（令和3年度 第3回 3／11）《厚生労働省》 |
ページ画像
ダウンロードした画像を利用する際は「出典情報」を明記してください。
低解像度画像をダウンロード
プレーンテキスト
資料テキストはコンピュータによる自動処理で生成されており、完全に資料と一致しない場合があります。
テキストをコピーしてご利用いただく際は資料と付け合わせてご確認ください。
研究報告の報告状況
(2021年8月1日～2021年11月30日)
NO 一般名
イコサペント酸エチル
75 イコサペント酸エチル含有一般
用医薬品
76 パロキセチン塩酸塩水和物
77 プロポフォール
78 ラベプラゾールナトリウム
79 フルボキサミンマレイン酸塩
80 アジスロマイシン水和物
ロサルタンカリウム・ヒドロクロロチ
アジド
ラベプラゾールナトリウム・アモキ
82 シシリン水和物・クラリスロマイシ
ン
81
83 バルプロ酸ナトリウム
84 リスペリドン
85 ラモトリギン
86
ロサルタンカリウム・ヒドロクロロチ
アジド
87 アジスロマイシン水和物
88
プロキシフィリン・エフェドリン塩
酸塩・フェノバルビタール配合剤
89 ハロペリドールデカン酸エステル
フルチカゾンプロピオン酸エステ
90 ル・ホルモテロールフマル酸塩水
和物
91
クエチアピンフマル酸塩
リスペリドン
92 バンコマイシン塩酸塩
93
ロサルタンカリウム・ヒドロクロロチ
アジド
94 アジスロマイシン水和物
95 パロキセチン塩酸塩水和物
96 デクスメデトミジン塩酸塩
97 エチゾラム
文献名
Embryo-toxicity of docosahexaenoic and eicosapentaenoic acids: In vivo and in silico investigations using
the chick embryo model
Zohreh Salari, Hadi Tavakkoli, Ahmad Khosravi, Elahe Karamad, Ehsan Salarkia, Mehdi Ansari, Shahriar
Dabiri, Abbas Mortazaeizdeh, Seyedeh Saedeh Mosallanejad, Fatemeh Sharifi
Biomedicine & pharmacotherapy(FRANCE)_Volume136_111218
Ulbrich, K.A. et al.. Acute delivery room resuscitation of neonates exposed to selective serotonin
reuptake inhibitors. J. Pediat.. 2021; 232: 103-108.e2.
He, Lin .Effects of embryonic propofol exposure on axonal growth and locomotor activity in
zebrafish.Journal of Applied Toxicology. 2020;40(6):855-863.
【Br J Clin Pharmacol. 87(2021)3150-3161】Proton pump inhibitors and risk of all-cause and causespecific mortality: A cohort study
Ulbrich K.A, Zumpf K, Ciolino J.D, Shah M, Miller E.S, Wisner K.L. Acute delivery room resuscitation of
neonates exposed to selective serotonin reuptake inhibitors. The Journal of Pediatrics. 2021;232:103108.e2.
Haghjoo M, Golipra R, Kheirkhah J, et al. Effect of COVID-19 medications on corrected QT interval and
induction of torsade de pointes: Results of a multicenter national survey. International Journal of Clinical
Practice. 2021;75(7):e14182.
Lecaros-Astorga, D.A. et al., Hydrochlorothiazide use and risk of non-melanoma skin cancer in Spain: A
case/non-case study, Int~l J. Clin. Pharmacol. Ther. 59(4),280-288,2021
Ify R. Mordi et al. Genetic and pharmacological relationship between P-glycoprotein and increased
cardiovascular risk associated with clarithromycin prescription: An epidemiological and genomic
population based cohort study in Scotland, UK. PLoS Medicine. 2020; 17(11): e1003372.
Thrombocytopenia during intravenous valproic acid therapy in the neurological intensive care
unit.Journal of clinical pharmacy and therapeutics, 2020, 45(5), 1014-1020
Gormus G, Ilgin S, Baysal M, et al. Risperidone induced reproductive toxicity in male rats targeting
leydig cells and hypothalamic-pituitary-gonadal axis by inducing oxidative stress. Andrologia.
2021;53(1):e13813.
Toshiki Fukasawa.Risk of Stevens-Johnson syndrome and toxic epidermal necrolysis associated with
anticonvulsants in a Japanese population: Matched case-control and cohort studies.Allergology
International 2021;70(30):335-342.
Drucker, A.M. et al. (University of Toronto, Ontario, Canada). Association between antihypertensive
medications and risk of skin cancer in people older than 65 years: a population-based study. CMAJ.
2021; 193(15): E508-E516-.
Haghjoo, M. et al. (Iran University of Medical Sciences, Tehran, Iran). Effect of COVID-19 medications
on corrected QT interval and induction of torsade de pointes: Results of a multicenter national survey.
Int'l J. Clin. Pract.. 2021; 75(7): e14182.
Chainirun N, et al..Assessing antiepileptic drugs in women with epilepsy during pregnancy in srinagarind
hospital, Khon Kaen University, Thailand..Journal of the Medical Association of Thailand
2021;104(2):S77-S80.
Cardiovascular Events Associated with Antipsychotics in Newly Diagnosed Parkinson’s Disease Patients:
A Propensity Score Matched Cohort Study
Chen, Hong 1 ; Feng, Yulin 2 ; Wang, Ke 2 ; Yang, Jing 2 ; Du, Yuejun 1. Association between inhaled
corticosteroids and upper respiratory tract infection in patients with chronic obstructive pulmonary
disease: a meta-analysis of randomized controlled trials. BMC pulmonary medicine. 2020; 20(1): 282-.
Psychotropic medication and cognitive, functional, and neuropsychiatric outcomes in Alzheimer's disease
(AD)
J.Am. Geriat. Soc. 2021,69(4),955-963
Impact of urinary albumin excretion on the onset of adverse reactions to vancomycin hydrochloride
Int'l J. Clin. Pharmacol. Ther. 2021,59(6),428-432
Association between antihypertensive medications and risk of skin cancer in people older than 65 years :
a population-based study
CMAJ 2021,193(15),E508-E516
Effect of COVID-19 medications on corrected QT interval and induction of torsade de pointes : Results
of a multicenter national survey
Int'l J. Clin. Pract. 2021,75(7),e14182
Ulbrich,K.A. et al.
Acute delivery room resuscitation of neonates exposed to selective serotonin reuptake inhibitors
J. Pediat. 2021,232,103-108.e2
Chen, P.. Dexmedetomidine promotes the progression of hepatocellular carcinoma through hepatic
stellate cell activation. Experimental & molecular medicine. 2020;52(7):1062-1074
Trends in Nonfatal and Fatal Overdoses Involving Benzodiazepines-38 States and the District of
Columbia, 2019-2020
沈降精製百日せきジフテリア破
傷風混合ワクチン
Miguel Elas et al. Disproportionality analysis of reported drug adverse events to assess a potential safety
98 沈降精製百日せきジフテリア破
signal for pentavalent vaccine in 2019 in El Salvador. Vaccine 2021.8.9;39(34):4849-4855.
傷風不活化ポリオ（セービン株）
混合ワクチン
Arnautovic, T.I. et al. (Tufts University School of Medicine, MA., USA). Antenatal risk factors associated
ベタメタゾン・ｄ－クロルフェニラミ
99
with spontaneous intestinal perforation in preterm infants receiving postnatal indomethacin. J. Pediat.
ンマレイン酸塩
2021; 232: 59-64.e1.
ゾルピデム酒石酸塩
高齢者の転倒に対するオレキシン受容体拮抗薬の関連性の検討 －ケース・クロスオーバー法を用いた
100
ブロチゾラム
後ろ向き解析調査－. Prog. Med.. 2021; 41(6): 565-572.
4
(2021年8月1日～2021年11月30日)
NO 一般名
イコサペント酸エチル
75 イコサペント酸エチル含有一般
用医薬品
76 パロキセチン塩酸塩水和物
77 プロポフォール
78 ラベプラゾールナトリウム
79 フルボキサミンマレイン酸塩
80 アジスロマイシン水和物
ロサルタンカリウム・ヒドロクロロチ
アジド
ラベプラゾールナトリウム・アモキ
82 シシリン水和物・クラリスロマイシ
ン
81
83 バルプロ酸ナトリウム
84 リスペリドン
85 ラモトリギン
86
ロサルタンカリウム・ヒドロクロロチ
アジド
87 アジスロマイシン水和物
88
プロキシフィリン・エフェドリン塩
酸塩・フェノバルビタール配合剤
89 ハロペリドールデカン酸エステル
フルチカゾンプロピオン酸エステ
90 ル・ホルモテロールフマル酸塩水
和物
91
クエチアピンフマル酸塩
リスペリドン
92 バンコマイシン塩酸塩
93
ロサルタンカリウム・ヒドロクロロチ
アジド
94 アジスロマイシン水和物
95 パロキセチン塩酸塩水和物
96 デクスメデトミジン塩酸塩
97 エチゾラム
文献名
Embryo-toxicity of docosahexaenoic and eicosapentaenoic acids: In vivo and in silico investigations using
the chick embryo model
Zohreh Salari, Hadi Tavakkoli, Ahmad Khosravi, Elahe Karamad, Ehsan Salarkia, Mehdi Ansari, Shahriar
Dabiri, Abbas Mortazaeizdeh, Seyedeh Saedeh Mosallanejad, Fatemeh Sharifi
Biomedicine & pharmacotherapy(FRANCE)_Volume136_111218
Ulbrich, K.A. et al.. Acute delivery room resuscitation of neonates exposed to selective serotonin
reuptake inhibitors. J. Pediat.. 2021; 232: 103-108.e2.
He, Lin .Effects of embryonic propofol exposure on axonal growth and locomotor activity in
zebrafish.Journal of Applied Toxicology. 2020;40(6):855-863.
【Br J Clin Pharmacol. 87(2021)3150-3161】Proton pump inhibitors and risk of all-cause and causespecific mortality: A cohort study
Ulbrich K.A, Zumpf K, Ciolino J.D, Shah M, Miller E.S, Wisner K.L. Acute delivery room resuscitation of
neonates exposed to selective serotonin reuptake inhibitors. The Journal of Pediatrics. 2021;232:103108.e2.
Haghjoo M, Golipra R, Kheirkhah J, et al. Effect of COVID-19 medications on corrected QT interval and
induction of torsade de pointes: Results of a multicenter national survey. International Journal of Clinical
Practice. 2021;75(7):e14182.
Lecaros-Astorga, D.A. et al., Hydrochlorothiazide use and risk of non-melanoma skin cancer in Spain: A
case/non-case study, Int~l J. Clin. Pharmacol. Ther. 59(4),280-288,2021
Ify R. Mordi et al. Genetic and pharmacological relationship between P-glycoprotein and increased
cardiovascular risk associated with clarithromycin prescription: An epidemiological and genomic
population based cohort study in Scotland, UK. PLoS Medicine. 2020; 17(11): e1003372.
Thrombocytopenia during intravenous valproic acid therapy in the neurological intensive care
unit.Journal of clinical pharmacy and therapeutics, 2020, 45(5), 1014-1020
Gormus G, Ilgin S, Baysal M, et al. Risperidone induced reproductive toxicity in male rats targeting
leydig cells and hypothalamic-pituitary-gonadal axis by inducing oxidative stress. Andrologia.
2021;53(1):e13813.
Toshiki Fukasawa.Risk of Stevens-Johnson syndrome and toxic epidermal necrolysis associated with
anticonvulsants in a Japanese population: Matched case-control and cohort studies.Allergology
International 2021;70(30):335-342.
Drucker, A.M. et al. (University of Toronto, Ontario, Canada). Association between antihypertensive
medications and risk of skin cancer in people older than 65 years: a population-based study. CMAJ.
2021; 193(15): E508-E516-.
Haghjoo, M. et al. (Iran University of Medical Sciences, Tehran, Iran). Effect of COVID-19 medications
on corrected QT interval and induction of torsade de pointes: Results of a multicenter national survey.
Int'l J. Clin. Pract.. 2021; 75(7): e14182.
Chainirun N, et al..Assessing antiepileptic drugs in women with epilepsy during pregnancy in srinagarind
hospital, Khon Kaen University, Thailand..Journal of the Medical Association of Thailand
2021;104(2):S77-S80.
Cardiovascular Events Associated with Antipsychotics in Newly Diagnosed Parkinson’s Disease Patients:
A Propensity Score Matched Cohort Study
Chen, Hong 1 ; Feng, Yulin 2 ; Wang, Ke 2 ; Yang, Jing 2 ; Du, Yuejun 1. Association between inhaled
corticosteroids and upper respiratory tract infection in patients with chronic obstructive pulmonary
disease: a meta-analysis of randomized controlled trials. BMC pulmonary medicine. 2020; 20(1): 282-.
Psychotropic medication and cognitive, functional, and neuropsychiatric outcomes in Alzheimer's disease
(AD)
J.Am. Geriat. Soc. 2021,69(4),955-963
Impact of urinary albumin excretion on the onset of adverse reactions to vancomycin hydrochloride
Int'l J. Clin. Pharmacol. Ther. 2021,59(6),428-432
Association between antihypertensive medications and risk of skin cancer in people older than 65 years :
a population-based study
CMAJ 2021,193(15),E508-E516
Effect of COVID-19 medications on corrected QT interval and induction of torsade de pointes : Results
of a multicenter national survey
Int'l J. Clin. Pract. 2021,75(7),e14182
Ulbrich,K.A. et al.
Acute delivery room resuscitation of neonates exposed to selective serotonin reuptake inhibitors
J. Pediat. 2021,232,103-108.e2
Chen, P.. Dexmedetomidine promotes the progression of hepatocellular carcinoma through hepatic
stellate cell activation. Experimental & molecular medicine. 2020;52(7):1062-1074
Trends in Nonfatal and Fatal Overdoses Involving Benzodiazepines-38 States and the District of
Columbia, 2019-2020
沈降精製百日せきジフテリア破
傷風混合ワクチン
Miguel Elas et al. Disproportionality analysis of reported drug adverse events to assess a potential safety
98 沈降精製百日せきジフテリア破
signal for pentavalent vaccine in 2019 in El Salvador. Vaccine 2021.8.9;39(34):4849-4855.
傷風不活化ポリオ（セービン株）
混合ワクチン
Arnautovic, T.I. et al. (Tufts University School of Medicine, MA., USA). Antenatal risk factors associated
ベタメタゾン・ｄ－クロルフェニラミ
99
with spontaneous intestinal perforation in preterm infants receiving postnatal indomethacin. J. Pediat.
ンマレイン酸塩
2021; 232: 59-64.e1.
ゾルピデム酒石酸塩
高齢者の転倒に対するオレキシン受容体拮抗薬の関連性の検討 －ケース・クロスオーバー法を用いた
100
ブロチゾラム
後ろ向き解析調査－. Prog. Med.. 2021; 41(6): 565-572.
4