よむ、つかう、まなぶ。
資料4-6 メトホルミン塩酸塩 (22 ページ)
出典
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Gynaecol Obstet 2015; 131: 111-6.
16） zum Einsatz von Metformin vor und während der Schwangerschaft bei Frauen mit PCOS und
Kinderwunsch 2015
17） Tso LO, et al. Metformin treatment before and during IVF or ICSI in women with polycystic
ovary syndrome. Cochrane Database Syst Rev 2014; 11: CD006105.
18） Corbett S, et al. The Prevention of Ovarian Hyperstimulation Syndrome. J Obstet Gynaecol Can
2014; 36: 1024-33.
19） Costello MF, et al. A systematic review and meta-analysis of randomized controlled trials on
metformin co-administration during gonadotrophin ovulation induction or IVF in women with
polycystic ovary syndrome. Hum Reprod 2006; 21: 1387-99.
20） Tso LO, et al. Metformin treatment before and during IVF or ICSI in women with polycystic
ovary syndrome. Cochrane Database Syst Rev 2009; 2: CD006105.
21） International evidence-based guideline for the assessment and management of polycystic ovary
syndrome 2018
22） Huang X, et al. A systematic review and meta-analysis of metformin among patients with
polycystic ovary syndrome undergoing assisted reproductive technology procedures. Int J
Gynaecol Obstet 2015; 131: 111-6.
23） Kjotrod SB, et al. Use of metformin before and during assisted reproductive technology in nonobese young infertile women with polycystic ovary syndrome: a prospective, randomized,
double-blind, multi-centre study. Hum Reprod 2011; 26: 2045-53.
24） Kjotrod SB, et al. Metformin treatment before IVF/ICSI in women with polycystic ovary
syndrome; a prospective, randomized, double blind study. Hum Reprod 2004; 19: 1315-22.
25） Fedorcsak P, et al. The effect of metformin on ovarian stimulation and in vitro fertilization in
insulin-resistant women with polycystic ovary syndrome: an open-label randomized cross-over
trial. Gynecol Endocrinol 2003; 17: 207-14.
26） Onalan G, et al. Metformin treatment in patients with polycystic ovary syndrome undergoing in
vitro fertilization: a prospective randomized trial. Fertil Steril 2005; 84: 798-801.
27） Panchaud A, et al. Use of metformin during pregnancy and risk of major congenital
malformations: Preliminary findings of a systematic review and meta-analysis. Reprod Toxicol
2019; 88: 149.
28） Diav-Citrin O, et al. In-utero exposure to metformin for type 2 diabetes or polycystic ovary
syndrome: A prospective comparative observational study. Reprod Toxicol 2018; 80: 85-91.
29） Scherneck S, et al. Pregnancy outcome after first-trimester exposure to metformin: A
prospective cohort study. Reprod Toxicol 2018; 81: 79-83.
30） Gilbert C, et al. Pregnancy outcome after first-trimester exposure to metformin: a meta-analysis.
Fertil Steril 2006; 86: 658-63
31） メトグルコ錠 250 mg 申請資料概要
22
16） zum Einsatz von Metformin vor und während der Schwangerschaft bei Frauen mit PCOS und
Kinderwunsch 2015
17） Tso LO, et al. Metformin treatment before and during IVF or ICSI in women with polycystic
ovary syndrome. Cochrane Database Syst Rev 2014; 11: CD006105.
18） Corbett S, et al. The Prevention of Ovarian Hyperstimulation Syndrome. J Obstet Gynaecol Can
2014; 36: 1024-33.
19） Costello MF, et al. A systematic review and meta-analysis of randomized controlled trials on
metformin co-administration during gonadotrophin ovulation induction or IVF in women with
polycystic ovary syndrome. Hum Reprod 2006; 21: 1387-99.
20） Tso LO, et al. Metformin treatment before and during IVF or ICSI in women with polycystic
ovary syndrome. Cochrane Database Syst Rev 2009; 2: CD006105.
21） International evidence-based guideline for the assessment and management of polycystic ovary
syndrome 2018
22） Huang X, et al. A systematic review and meta-analysis of metformin among patients with
polycystic ovary syndrome undergoing assisted reproductive technology procedures. Int J
Gynaecol Obstet 2015; 131: 111-6.
23） Kjotrod SB, et al. Use of metformin before and during assisted reproductive technology in nonobese young infertile women with polycystic ovary syndrome: a prospective, randomized,
double-blind, multi-centre study. Hum Reprod 2011; 26: 2045-53.
24） Kjotrod SB, et al. Metformin treatment before IVF/ICSI in women with polycystic ovary
syndrome; a prospective, randomized, double blind study. Hum Reprod 2004; 19: 1315-22.
25） Fedorcsak P, et al. The effect of metformin on ovarian stimulation and in vitro fertilization in
insulin-resistant women with polycystic ovary syndrome: an open-label randomized cross-over
trial. Gynecol Endocrinol 2003; 17: 207-14.
26） Onalan G, et al. Metformin treatment in patients with polycystic ovary syndrome undergoing in
vitro fertilization: a prospective randomized trial. Fertil Steril 2005; 84: 798-801.
27） Panchaud A, et al. Use of metformin during pregnancy and risk of major congenital
malformations: Preliminary findings of a systematic review and meta-analysis. Reprod Toxicol
2019; 88: 149.
28） Diav-Citrin O, et al. In-utero exposure to metformin for type 2 diabetes or polycystic ovary
syndrome: A prospective comparative observational study. Reprod Toxicol 2018; 80: 85-91.
29） Scherneck S, et al. Pregnancy outcome after first-trimester exposure to metformin: A
prospective cohort study. Reprod Toxicol 2018; 81: 79-83.
30） Gilbert C, et al. Pregnancy outcome after first-trimester exposure to metformin: a meta-analysis.
Fertil Steril 2006; 86: 658-63
31） メトグルコ錠 250 mg 申請資料概要
22