よむ、つかう、まなぶ。
資料4-2 レベチラセタム (16 ページ)
出典
| 公開元URL | https://www.mhlw.go.jp/stf/shingi2/0000198856_00023.html |
| 出典情報 | 医療上の必要性の高い未承認薬・適応外薬検討会議（第51回 6／8）《厚生労働省》 |
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１０．備考
なし。
１１．参考文献一覧
1)
Trinka E, et al. A definition and classification of status epilepticus – Report of the ILAE Task
Force on Classification of Status Epilepticus. Epilepsia 2015; 56: 1515-23.
2)
Alldredge BK, et al. A comparison of lorazepam, diazepam, and placebo for the treatment of outof-hospital Status Epilepticus. N Engl J Med 2001; 345: 631-7.
3)
てんかん診療ガイドライン 2018. 医学書院; 2018.、てんかん診療ガイドライン 2018 追
補版. https://neurology-jp.org/guidelinem/epgl/tenkan_2018_tuiho_cq8-2.pdf（最終確認日：
2022 年 3 月）
4)
Neurocritical Care Society Guidelines for the Evaluation and Management of Status Epi
lepticus. https://higherlogicdownload.s3.amazonaws.com/NEUROCRITICALCARE/b8b3b38
4-bfb9-42af-bb55-45973d5054a4/UploadedImages/Documents/Guidelines/SE_Guidelines_NC
S_0412.pdf（最終確認日：2022 年 3 月）
5)
NHS Foundation Trust "Guideline for the Management of Generalised Convulsive Status
Epilepticus in Adults"
6)
H Meierkord, et al. EFNS guideline on the management of status epilepticus in adults. Eur J
Neurol 2010; 17: 348-55.
7)
H Outin, et al. Management of status epilepticus in the prehospital setting, in the emergency
department and in intensive care unit. Ann Fr Med Urgence 2020; 10: 151-86.
8)
Helman A, et al. Emergency Management of Status Epilepticus. Emergency Medicine Cases.
December, 2019. https://emergencymedicinecases.com/status-epilepticus. （最終確認日：2022
年 3 月）
9)
Jones CL, Koios J. Algorithm for the treatment of status epilepticus: an Australian perspective.
Intern Med J 2016; 46: 500-3.
10) Kapur J, et al. Randomized Trial of Three Anticonvulsant Medications for Status Epilepticus. N
Engl J Med 2019; 381: 2103-13.
11) Chamberlain JM, et al. Efficacy of levetiracetam, fosphenytoin, and valproate for established
status epilepticus by age group (ESETT): a double-blind, responsive-adaptive, randomised
controlled trial. Lancet 2020; 395: 1217-24.
12) Eue S, et al. Two years of experience in the treatment of status epilepticus with intravenous
levetiracetam. Epilepsy Behav 2009; 15: 467-9.
13) Alvarez V, et al. Second-line status epilepticus treatment: comparison of phenytoin, valproate,
and levetiracetam. Epilepsia 2011; 52: 1292-6.
14) Tripathi M, et al. Management of refractory status epilepticus at a tertiary care centre in a
16
なし。
１１．参考文献一覧
1)
Trinka E, et al. A definition and classification of status epilepticus – Report of the ILAE Task
Force on Classification of Status Epilepticus. Epilepsia 2015; 56: 1515-23.
2)
Alldredge BK, et al. A comparison of lorazepam, diazepam, and placebo for the treatment of outof-hospital Status Epilepticus. N Engl J Med 2001; 345: 631-7.
3)
てんかん診療ガイドライン 2018. 医学書院; 2018.、てんかん診療ガイドライン 2018 追
補版. https://neurology-jp.org/guidelinem/epgl/tenkan_2018_tuiho_cq8-2.pdf（最終確認日：
2022 年 3 月）
4)
Neurocritical Care Society Guidelines for the Evaluation and Management of Status Epi
lepticus. https://higherlogicdownload.s3.amazonaws.com/NEUROCRITICALCARE/b8b3b38
4-bfb9-42af-bb55-45973d5054a4/UploadedImages/Documents/Guidelines/SE_Guidelines_NC
S_0412.pdf（最終確認日：2022 年 3 月）
5)
NHS Foundation Trust "Guideline for the Management of Generalised Convulsive Status
Epilepticus in Adults"
6)
H Meierkord, et al. EFNS guideline on the management of status epilepticus in adults. Eur J
Neurol 2010; 17: 348-55.
7)
H Outin, et al. Management of status epilepticus in the prehospital setting, in the emergency
department and in intensive care unit. Ann Fr Med Urgence 2020; 10: 151-86.
8)
Helman A, et al. Emergency Management of Status Epilepticus. Emergency Medicine Cases.
December, 2019. https://emergencymedicinecases.com/status-epilepticus. （最終確認日：2022
年 3 月）
9)
Jones CL, Koios J. Algorithm for the treatment of status epilepticus: an Australian perspective.
Intern Med J 2016; 46: 500-3.
10) Kapur J, et al. Randomized Trial of Three Anticonvulsant Medications for Status Epilepticus. N
Engl J Med 2019; 381: 2103-13.
11) Chamberlain JM, et al. Efficacy of levetiracetam, fosphenytoin, and valproate for established
status epilepticus by age group (ESETT): a double-blind, responsive-adaptive, randomised
controlled trial. Lancet 2020; 395: 1217-24.
12) Eue S, et al. Two years of experience in the treatment of status epilepticus with intravenous
levetiracetam. Epilepsy Behav 2009; 15: 467-9.
13) Alvarez V, et al. Second-line status epilepticus treatment: comparison of phenytoin, valproate,
and levetiracetam. Epilepsia 2011; 52: 1292-6.
14) Tripathi M, et al. Management of refractory status epilepticus at a tertiary care centre in a
16