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参考資料２ 高病原性鳥インフルエンザウイルスA(H5N1)感染事例に関するリスクアセスメントと対応 (22 ページ)
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国立健康危機管理研究機構
高病原性鳥インフルエンザウイルス A(H5N1)感染事例に関するリスクアセスメントと対応
disease-threats-report-week-5-2025.pdf. 2025b
•
Eisfeld AJ, Biswas A, Guan L, et al. Pathogenicity and transmissibility of bovine
H5N1 influenza virus. Nature. 2024;633(8029):426-432. doi:10.1038/s41586024-07766-6
•
Gao Y, Zhang Y, Shinya K, et al. Identification of amino acids in HA and PB2
critical for the transmission of H5N1 avian influenza viruses in a mammalian
host. PLoS Pathog. 2009;5(12):e1000709. doi:10.1371/journal.ppat.1000709
•
GISAID. As of 13 February 2024. https://gisaid.org/. 2024
•
GISAID. AS of 4 March 2025. https://gisaid.org/. 2025
•
Hatta M, Hatta Y, Kim JH, et al. Growth of H5N1 influenza A viruses in the upper
respiratory tracts of mice. PLoS Pathog. 2007;3(10):1374-1379.
doi:10.1371/journal.ppat.0030133
•
Herfst S, Schrauwen EJ, Linster M, et al. Airborne transmission of influenza
A/H5N1 virus between ferrets. Science. 2012;336(6088):1534-1541.
doi:10.1126/science.1213362
•
Hiono T, Kobayashi D, Kobayashi A, et al. Virological, pathological, and
glycovirological investigations of an Ezo red fox and a tanuki naturally infected
with H5N1 high pathogenicity avian influenza viruses in Hokkaido, Japan.
Virology. 2023;578:35-44. doi:10.1016/j.virol.2022.11.008
•
Hu X, Saxena A, Magstadt DR, et al. Genomic characterization of highly
pathogenic avian influenza A H5N1 virus newly emerged in dairy cattle. Emerg
Microbes Infect. 2024;13(1):2380421. doi:10.1080/22221751.2024.2380421
•
Kong H, Ma S, Wang J, et al. Identification of Key Amino Acids in the PB2 and
M1 Proteins of H7N9 Influenza Virus That Affect Its Transmission in Guinea
Pigs. J Virol. 2019;94(1):e01180-19. Published 2019 Dec 12.
doi:10.1128/JVI.01180-19
•
Kim Y, Fournié G, Métras R, et al. Lessons for cross-species viral transmission
surveillance from highly pathogenic avian influenza Korean cat shelter
outbreaks. Nat Commun. 2023;14(1):6958. Published 2023 Oct 31.
doi:10.1038/s41467-023-42738-w
•
Kuiken T, Rimmelzwaan G, van Riel D, et al. Avian H5N1 influenza in cats.
Science. 2004;306(5694):241. doi:10.1126/science.1102287
•
Leguia M, Garcia-Glaessner A, Muñoz-Saavedra B, et al. Highly pathogenic avian
influenza A (H5N1) in marine mammals and seabirds in Peru. Nat Commun.
2023;14(1):5489. Published 2023 Sep 7. doi:10.1038/s41467-023-41182-0
•
Minnesota Board of Animal Health, Stevens County goat tests positive for same
©National Institute of Infectious Diseases, Tokyo, Japan, 2023-2024
©Japan Institute for Health Security, Tokyo, Japan, 2025
22 / 29
高病原性鳥インフルエンザウイルス A(H5N1)感染事例に関するリスクアセスメントと対応
disease-threats-report-week-5-2025.pdf. 2025b
•
Eisfeld AJ, Biswas A, Guan L, et al. Pathogenicity and transmissibility of bovine
H5N1 influenza virus. Nature. 2024;633(8029):426-432. doi:10.1038/s41586024-07766-6
•
Gao Y, Zhang Y, Shinya K, et al. Identification of amino acids in HA and PB2
critical for the transmission of H5N1 avian influenza viruses in a mammalian
host. PLoS Pathog. 2009;5(12):e1000709. doi:10.1371/journal.ppat.1000709
•
GISAID. As of 13 February 2024. https://gisaid.org/. 2024
•
GISAID. AS of 4 March 2025. https://gisaid.org/. 2025
•
Hatta M, Hatta Y, Kim JH, et al. Growth of H5N1 influenza A viruses in the upper
respiratory tracts of mice. PLoS Pathog. 2007;3(10):1374-1379.
doi:10.1371/journal.ppat.0030133
•
Herfst S, Schrauwen EJ, Linster M, et al. Airborne transmission of influenza
A/H5N1 virus between ferrets. Science. 2012;336(6088):1534-1541.
doi:10.1126/science.1213362
•
Hiono T, Kobayashi D, Kobayashi A, et al. Virological, pathological, and
glycovirological investigations of an Ezo red fox and a tanuki naturally infected
with H5N1 high pathogenicity avian influenza viruses in Hokkaido, Japan.
Virology. 2023;578:35-44. doi:10.1016/j.virol.2022.11.008
•
Hu X, Saxena A, Magstadt DR, et al. Genomic characterization of highly
pathogenic avian influenza A H5N1 virus newly emerged in dairy cattle. Emerg
Microbes Infect. 2024;13(1):2380421. doi:10.1080/22221751.2024.2380421
•
Kong H, Ma S, Wang J, et al. Identification of Key Amino Acids in the PB2 and
M1 Proteins of H7N9 Influenza Virus That Affect Its Transmission in Guinea
Pigs. J Virol. 2019;94(1):e01180-19. Published 2019 Dec 12.
doi:10.1128/JVI.01180-19
•
Kim Y, Fournié G, Métras R, et al. Lessons for cross-species viral transmission
surveillance from highly pathogenic avian influenza Korean cat shelter
outbreaks. Nat Commun. 2023;14(1):6958. Published 2023 Oct 31.
doi:10.1038/s41467-023-42738-w
•
Kuiken T, Rimmelzwaan G, van Riel D, et al. Avian H5N1 influenza in cats.
Science. 2004;306(5694):241. doi:10.1126/science.1102287
•
Leguia M, Garcia-Glaessner A, Muñoz-Saavedra B, et al. Highly pathogenic avian
influenza A (H5N1) in marine mammals and seabirds in Peru. Nat Commun.
2023;14(1):5489. Published 2023 Sep 7. doi:10.1038/s41467-023-41182-0
•
Minnesota Board of Animal Health, Stevens County goat tests positive for same
©National Institute of Infectious Diseases, Tokyo, Japan, 2023-2024
©Japan Institute for Health Security, Tokyo, Japan, 2025
22 / 29