よむ、つかう、まなぶ。
【参考資料3】【英版R4.1.17】Nippon AMR One Health Report (NAOR) 2020 (14 ページ)
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出典情報 | 国際的に脅威となる感染症対策関係閣僚会議 薬剤耐性ワンヘルス動向調査検討会(第9回 1/17)《厚生労働省》 |
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ⅱ. Klebsiella pneumoniae
Table 2. Trends in the proportion (%) of antimicrobial-resistant Klebsiella pneumoniae
ABPC
BP
(-2013)
32
BP
(2014-)
32
PIPC
128
128
TAZ/
PIPC
CEZ*
4/128
4/128
32
8
CMZ
64
64
CTX*
64
4
CAZ*
32
16
CFPM
32
32
AZT*
32
16
IPM*
16
4
MEPM*
16
4
AMK
64
64
LVFX
8
8
2011
2012
2013
2014
2015
2016
2017
2018
2019
75.9
(65,338)
19.7
(67,548)
-
76.9
(73,078)
20.1
(74,878)
-
8.8
(68,481)
-
9.0
(76,860)
-
77.8
(80,030)
24.3
(82,608)
2.2
(27,279)
9.1
(85,320)
-
5.2
(56,236)
3.4
(68,916)
-
5.4
(62,242)2.9
(76,961)
-
4.1
(54,680)
0.2
(63,825)
-
3.7
(60,606)
0.2
(70,284)
-
0.3
(68,995)
2.7
(66,466)
0.2
(76,293)
2.4
(74,718)
76.3
(90,220)
21.9
(91,761)
2.0
(46,941)
11.7
(94,875)
1.9
(85,749)
8.6
(73,574)
3.8
(94,878)
3.5
(66,399)
5.1
(75,340)
0.3
(85,253)
0.6
(73,903)
0.1
(95,643)
2.4
(92,993)
76.9
(131,700)
21.1
(136,347)
2.0
(91,503)
12.1
(135,486)
1.9
(132,163)
8.0
(107,409)
4.0
(138,191)
4.0
(119,563)
5.3
(110,259)
0.3
(126,997)
0.6
(135,930)
0.1
(141,710)
2.6
(138,428)
76.3
(147,500)
21.8
(154,260)
2.2
(110,189)
13.1
(152,973)
1.7
(152,086)
8.9
(118,057)
4.6
(155,293)
4.8
(138,737)
5.9
(122,600)
0.2
(143,813)
0.5
(159.623)
0.1
(159,871)
2.7
(156,249)
77.4
(152,477)
21.8
(161,254)
2.2
(118,796)
13.4
(157,849)
1.5
(159,375)
8.9
(119,672)
5.0
(160,619)
5.1
(145,745)
6.2
(127,491)
0.2
(149,546)
0.4
(166,298)
0.1
(166.081)
2.8
(163,688)
79.4
(158,654)
22.9
(165,430)
2.6
(127,778)
14.3
(166,906)
1.6
(168,787)
9.4
(122,459)
5.7
(169,097)
5.8
(156,485)
6.7
(133,009)
0.3
(154,879)
0.5
(175,408)
0.1
(174,259)
3.1
(172,010)
80.1
(159,790)
24.5
(161,590)
3.1
(135,732)
15.2
(170,001)
1.5
(172,912)
9.7
(122,241)
6.9
(173,031)
6.8
(160,502)
8.0
(135,631)
0.2
(155,242)
0.4
(179,042)
0.1
(176,609)
3.4
(175,799)
5.1
(66,654)
2.7
(84,761)
3.0
(41,143)
3.5
(67,253)
0.1
(77,193)
0.2
(48,190)
0.2
(84,916)
2.5
(83,063)
The unit of BP is μg/mL.
Figures in parentheses indicate the number of bacterial strains that were tested for antimicrobial susceptibility. Not under surveillance
* CLSI (2007) (M100-S17) Criteria was applied to determine the BP up to 2013. CLSI (2012) (M100-S22) Criteria was applied to determine BP after 2014.
ⅲ. Enterobacter spp.
Table 3. Trends in the proportion (%) of antimicrobial
ABPC
BP (-2013)
32
BP (2014-)
32
PIPC
128
128
TAZ/
PIPC
CEZ*
4/128
4/128
32
8
-
64
CTX*
64
4
CAZ*
32
16
CFPM
32
32
AZT*
32
16
IPM*
16
4
MEPM*
16
4
AMK
64
64
LVFX
8
8
CMZ**
2013
80.9
(35,849)
20.6
(36,988)
10.3
(11,895)
97.2
(37,359)
19.2
(30,106)
20.6
(37,202)
4.2
(17,900)
16.8
(29,460)
0.4
(34,403)
0.6
(21,164)
0.4
(37,947)
4.2
(37,274)
2014
79.0
(39,344)
20.0
(39,636)
8.6
(21,091)
98.2
(41,422)
83.4
(37,492)
31.1
(32,718)
24.7
(41,456)
4.2
(29,836)
23.8
(33,551)
1.6
(37,396)
1.3
(32,589)
0.2
(42,005)
3.5
(40,942)
2015
80.2
(55,960)
19.8
(58,039)
8.9
(40,315)
98.3
(58,637)
85.4
(56,647)
31.6
(46,727)
25.0
(59,533)
4.2
(52,218)
24.0
(48,570)
1.3
(54,926)
1.4
(59,009)
0.2
(61,086)
3.7
(59,393)
-resistant Enterobacter cloacae
2016
79.3
(61,667)
20.1
(63,580)
8.9
(47,390)
98.3
(64,634)
85.5
(63,331)
31.2
(50,311)
24.9
(65,317)
4.0
(58,298)
23.9
(52,951)
1.2
(60,602)
1.2
(67,250)
0.1
(67,133)
3.4
(65,161)
2017
79.8
(61,970)
20.8
(64,217)
9.4
(48,775)
98.3
(64,693)
86.1
(64,158)
32.4
(50,022)
25.8
(65,027)
4.0
(59,398)
24.3
(53,374)
1.1
(60,689)
1.1
(67,392)
0.1
(67,125)
3.5
(65,690)
2018
81.2
(64,820)
21.2
(66,020)
9.8
(52,186)
98.3
(68,017)
88.0
(68,013)
32.9
(51,470)
26.3
(68,737)
3.9
(64,337)
24.9
(55,988)
1.1
(63,611)
1.1
(71,119)
0.1
(70,659)
3.2
(69,392)
2019
81.3
(64,723)
21.7
(62,798)
10.5
(54,305)
98.2
(68,074)
87.4
(68,727)
33.7
(50,606)
26.8
(69,265)
4.0
(65,211)
26.1
(56,211)
1.2
(61,918)
0.9
(71,548)
0.1
(70,392)
3.1
(70,034)
The unit of BP is μg/mL.
Figures in parentheses indicate the number of bacterial strains that were tested for antimicrobial susceptibility.
-: Not under surveillance
* CLSI (2007) (M100-S17) Criteria was applied to determine the BP up to 2013. CLSI (2012) (M100-S22) Criteria was applied to determine BP after 2014.
13
Table 2. Trends in the proportion (%) of antimicrobial-resistant Klebsiella pneumoniae
ABPC
BP
(-2013)
32
BP
(2014-)
32
PIPC
128
128
TAZ/
PIPC
CEZ*
4/128
4/128
32
8
CMZ
64
64
CTX*
64
4
CAZ*
32
16
CFPM
32
32
AZT*
32
16
IPM*
16
4
MEPM*
16
4
AMK
64
64
LVFX
8
8
2011
2012
2013
2014
2015
2016
2017
2018
2019
75.9
(65,338)
19.7
(67,548)
-
76.9
(73,078)
20.1
(74,878)
-
8.8
(68,481)
-
9.0
(76,860)
-
77.8
(80,030)
24.3
(82,608)
2.2
(27,279)
9.1
(85,320)
-
5.2
(56,236)
3.4
(68,916)
-
5.4
(62,242)2.9
(76,961)
-
4.1
(54,680)
0.2
(63,825)
-
3.7
(60,606)
0.2
(70,284)
-
0.3
(68,995)
2.7
(66,466)
0.2
(76,293)
2.4
(74,718)
76.3
(90,220)
21.9
(91,761)
2.0
(46,941)
11.7
(94,875)
1.9
(85,749)
8.6
(73,574)
3.8
(94,878)
3.5
(66,399)
5.1
(75,340)
0.3
(85,253)
0.6
(73,903)
0.1
(95,643)
2.4
(92,993)
76.9
(131,700)
21.1
(136,347)
2.0
(91,503)
12.1
(135,486)
1.9
(132,163)
8.0
(107,409)
4.0
(138,191)
4.0
(119,563)
5.3
(110,259)
0.3
(126,997)
0.6
(135,930)
0.1
(141,710)
2.6
(138,428)
76.3
(147,500)
21.8
(154,260)
2.2
(110,189)
13.1
(152,973)
1.7
(152,086)
8.9
(118,057)
4.6
(155,293)
4.8
(138,737)
5.9
(122,600)
0.2
(143,813)
0.5
(159.623)
0.1
(159,871)
2.7
(156,249)
77.4
(152,477)
21.8
(161,254)
2.2
(118,796)
13.4
(157,849)
1.5
(159,375)
8.9
(119,672)
5.0
(160,619)
5.1
(145,745)
6.2
(127,491)
0.2
(149,546)
0.4
(166,298)
0.1
(166.081)
2.8
(163,688)
79.4
(158,654)
22.9
(165,430)
2.6
(127,778)
14.3
(166,906)
1.6
(168,787)
9.4
(122,459)
5.7
(169,097)
5.8
(156,485)
6.7
(133,009)
0.3
(154,879)
0.5
(175,408)
0.1
(174,259)
3.1
(172,010)
80.1
(159,790)
24.5
(161,590)
3.1
(135,732)
15.2
(170,001)
1.5
(172,912)
9.7
(122,241)
6.9
(173,031)
6.8
(160,502)
8.0
(135,631)
0.2
(155,242)
0.4
(179,042)
0.1
(176,609)
3.4
(175,799)
5.1
(66,654)
2.7
(84,761)
3.0
(41,143)
3.5
(67,253)
0.1
(77,193)
0.2
(48,190)
0.2
(84,916)
2.5
(83,063)
The unit of BP is μg/mL.
Figures in parentheses indicate the number of bacterial strains that were tested for antimicrobial susceptibility. Not under surveillance
* CLSI (2007) (M100-S17) Criteria was applied to determine the BP up to 2013. CLSI (2012) (M100-S22) Criteria was applied to determine BP after 2014.
ⅲ. Enterobacter spp.
Table 3. Trends in the proportion (%) of antimicrobial
ABPC
BP (-2013)
32
BP (2014-)
32
PIPC
128
128
TAZ/
PIPC
CEZ*
4/128
4/128
32
8
-
64
CTX*
64
4
CAZ*
32
16
CFPM
32
32
AZT*
32
16
IPM*
16
4
MEPM*
16
4
AMK
64
64
LVFX
8
8
CMZ**
2013
80.9
(35,849)
20.6
(36,988)
10.3
(11,895)
97.2
(37,359)
19.2
(30,106)
20.6
(37,202)
4.2
(17,900)
16.8
(29,460)
0.4
(34,403)
0.6
(21,164)
0.4
(37,947)
4.2
(37,274)
2014
79.0
(39,344)
20.0
(39,636)
8.6
(21,091)
98.2
(41,422)
83.4
(37,492)
31.1
(32,718)
24.7
(41,456)
4.2
(29,836)
23.8
(33,551)
1.6
(37,396)
1.3
(32,589)
0.2
(42,005)
3.5
(40,942)
2015
80.2
(55,960)
19.8
(58,039)
8.9
(40,315)
98.3
(58,637)
85.4
(56,647)
31.6
(46,727)
25.0
(59,533)
4.2
(52,218)
24.0
(48,570)
1.3
(54,926)
1.4
(59,009)
0.2
(61,086)
3.7
(59,393)
-resistant Enterobacter cloacae
2016
79.3
(61,667)
20.1
(63,580)
8.9
(47,390)
98.3
(64,634)
85.5
(63,331)
31.2
(50,311)
24.9
(65,317)
4.0
(58,298)
23.9
(52,951)
1.2
(60,602)
1.2
(67,250)
0.1
(67,133)
3.4
(65,161)
2017
79.8
(61,970)
20.8
(64,217)
9.4
(48,775)
98.3
(64,693)
86.1
(64,158)
32.4
(50,022)
25.8
(65,027)
4.0
(59,398)
24.3
(53,374)
1.1
(60,689)
1.1
(67,392)
0.1
(67,125)
3.5
(65,690)
2018
81.2
(64,820)
21.2
(66,020)
9.8
(52,186)
98.3
(68,017)
88.0
(68,013)
32.9
(51,470)
26.3
(68,737)
3.9
(64,337)
24.9
(55,988)
1.1
(63,611)
1.1
(71,119)
0.1
(70,659)
3.2
(69,392)
2019
81.3
(64,723)
21.7
(62,798)
10.5
(54,305)
98.2
(68,074)
87.4
(68,727)
33.7
(50,606)
26.8
(69,265)
4.0
(65,211)
26.1
(56,211)
1.2
(61,918)
0.9
(71,548)
0.1
(70,392)
3.1
(70,034)
The unit of BP is μg/mL.
Figures in parentheses indicate the number of bacterial strains that were tested for antimicrobial susceptibility.
-: Not under surveillance
* CLSI (2007) (M100-S17) Criteria was applied to determine the BP up to 2013. CLSI (2012) (M100-S22) Criteria was applied to determine BP after 2014.
13