よむ、つかう、まなぶ。
【参考資料３】【英版R4.1.17】Nippon AMR One Health Report (NAOR) 2020 (51 ページ)
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Table 62. Resistance rates of Escherichia coli derived from diseased dogs and cats (%)
Agent
BP
＊
ABPC
32
CEZ
32＊
CEX
32†
CTX
4＊
MEPM
4＊
SM
32†
GM
16＊
KM
64＊
TC
16＊
CP
32＊
CL
4＊
NA
32＊
CPFX
4＊
ST
76/4＊
Strains tested (n)
Animal
Dogs
Cats
Dogs
Cats
Dogs
Cats
Dogs
Cats
Dogs
Cats
Dogs
Cats
Dogs
Cats
Dogs
Cats
Dogs
Cats
Dogs
Cats
Dogs
Cats
Dogs
Cats
Dogs
Cats
Dogs
Cats
Dogs
Cats
2017
55.3
64.0
31.2
37.5
31.7
41.9
26.1
33.8
0.0
0.0
29.6
32.4
14.1
12.5
6.5
8.1
28.1
24.3
12.6
13.2
1.0
0.0
61.8
58.8
43.2
39.0
24.6
22.1
199
136
2018
63.0
65.6
47.4
49.5
42.9
47.3
41.6
40.9
0.0
0.0
29.9
34.4
18.8
15.1
7.8
12.9
27.3
28.0
16.9
15.1
0.6
0.0
72.7
68.8
55.2
50.5
27.9
34.4
154
93
2019
51.1
60.2
30.3
32.0
31.5
31.3
26.4
26.6
0.0
0.0
20.2
28.9
12.9
9.4
5.1
7.0
21.3
26.6
11.8
7.8
0.0
0.0
56.2
46.9
38.8
37.5
17.4
22.7
178
128
The unit of BP is μg/mL.
* BP follows CLSI Criteria.
†
BP follows EUCAST Criteria.
ⅱ. Klebsiella spp.
Monitoring of 13 agents was carried out. Of the Klebsiella spp., K. pneumoniae was the most commonly
collected, followed by K. oxytoca. In 2019, resistance to CEZ, CEX, NA, and CPFX was observed to exceed 40%
in dog- and cat-derived strains, as was resistance to CTX, SM, GM, TC, and ST in cat-derived strains. On the other
hand, resistance to KM was below 20% in strains derived from both dogs and cats. Looking at rates of resistance
to critically important antimicrobials for human medicine, resistance to CTX was 34.6-56.8%, and resistance to
CPFX was 46.9-75.7%. No resistance to CL and MEPM was observed.
50
Agent
BP
＊
ABPC
32
CEZ
32＊
CEX
32†
CTX
4＊
MEPM
4＊
SM
32†
GM
16＊
KM
64＊
TC
16＊
CP
32＊
CL
4＊
NA
32＊
CPFX
4＊
ST
76/4＊
Strains tested (n)
Animal
Dogs
Cats
Dogs
Cats
Dogs
Cats
Dogs
Cats
Dogs
Cats
Dogs
Cats
Dogs
Cats
Dogs
Cats
Dogs
Cats
Dogs
Cats
Dogs
Cats
Dogs
Cats
Dogs
Cats
Dogs
Cats
Dogs
Cats
2017
55.3
64.0
31.2
37.5
31.7
41.9
26.1
33.8
0.0
0.0
29.6
32.4
14.1
12.5
6.5
8.1
28.1
24.3
12.6
13.2
1.0
0.0
61.8
58.8
43.2
39.0
24.6
22.1
199
136
2018
63.0
65.6
47.4
49.5
42.9
47.3
41.6
40.9
0.0
0.0
29.9
34.4
18.8
15.1
7.8
12.9
27.3
28.0
16.9
15.1
0.6
0.0
72.7
68.8
55.2
50.5
27.9
34.4
154
93
2019
51.1
60.2
30.3
32.0
31.5
31.3
26.4
26.6
0.0
0.0
20.2
28.9
12.9
9.4
5.1
7.0
21.3
26.6
11.8
7.8
0.0
0.0
56.2
46.9
38.8
37.5
17.4
22.7
178
128
The unit of BP is μg/mL.
* BP follows CLSI Criteria.
†
BP follows EUCAST Criteria.
ⅱ. Klebsiella spp.
Monitoring of 13 agents was carried out. Of the Klebsiella spp., K. pneumoniae was the most commonly
collected, followed by K. oxytoca. In 2019, resistance to CEZ, CEX, NA, and CPFX was observed to exceed 40%
in dog- and cat-derived strains, as was resistance to CTX, SM, GM, TC, and ST in cat-derived strains. On the other
hand, resistance to KM was below 20% in strains derived from both dogs and cats. Looking at rates of resistance
to critically important antimicrobials for human medicine, resistance to CTX was 34.6-56.8%, and resistance to
CPFX was 46.9-75.7%. No resistance to CL and MEPM was observed.
50