Glycopeptides
Oxazolidinones
Polypeptides

Lipopeptides
Amphenicols

Other antibacterial agents

Antitubercular antibiotics

◎prulifloxacin
◎moxifloxacin
◎garenoxacin
◎sitafloxacin
◎ofloxacin
◎enrofloxacin
oxolinic acid
nalidixic acid
vancomycin
teicoplanin
linezolid
polymyxin B
colistin
bacitracin
Daptomycin
chloramphenicol
florfenicol

PUFX
MFLX
GRNX
STFX
OFLX
ERFX
OA
NA
VCM
TEIC
LZD
PL-B
CL
BC
DAP
CP
FF

fosfomycin

FOM

salinomycin

SNM

bicozamycin

BCM

trimethoprim

TMP

isoniazid

INH

ethambutol

EB

rifampicin (rifampin)
pyrazinamide

RFP
PZA

rifabutin

RBT

* Quoted from the Glossary of Antimicrobial Chemotherapy (Japanese Society of Chemotherapy), the Annual Report of the Japanese
Society of Antimicrobials for Animals 36 (2014), and the Guidelines for the Use of Antimicrobial Substances in Cooperative
Livestock Insurances (2009, Ministry of Agriculture, Forestry and Fisheries)

[Reference] There are multiple relevant terminologies with different definitions. However, in medical practice, the
following four terms are often used interchangeably to refer drugs that act against bacteria: “antimicrobial
agents,” “antibiotics,” “antibiotic agents,” and “antibacterial agents.” In the areas of agriculture and livestock,
the expressions "antibacterial agents" and "antimicrobial agents" are commonly used, because these agents are
not only used for therapeutic purposes, but also in antibiotic feed additives.
Antimicrobial agents or antimicrobials: Antimicrobial agents, or antimicrobials, are active against microorganisms,
which are generally categorized into bacteria, fungi, viruses and parasites. These are the general term for drugs to treat
and prevent infectious diseases. They contain antibacterial agents, antifungal agents, antiviral agents and antiparasitic
agents.
Antibacterial agents: Antimicrobial agents that are active against bacteria.
Antibiotics: informally defined as an agent that is derived from living organisms to inhibit and control cell activities of
microorganisms
Antibiotic agents: Another term for drugs that use the antibacterial action of antibiotics
Reference: the Manual of Antimicrobial Stewardship, 1st edition

In terms of active ingredients (veterinary drugs), in terms of effective value (antibiotic feed additives), in terms of
active ingredients (agrochemicals), antimicrobial consumption in terms of potency by weight (humans): All
these terms refer to active ingredient weight. Quantities in terms of the weight of active ingredients in veterinary
drugs are calculated from sales data collected from marketing authorization holders for the volume of each drug sold.
When doing so, the marketing authorization holders also submit estimates of the percentage of sales for each species
of domestic animal, so the estimated volumes sold are calculated for each species based on those estimated
percentages. As with the figures for veterinary drugs, quantities of antibiotic feed additives in terms of effective value,
quantities of agrochemicals in terms of active ingredients, and human antimicrobial consumption in terms of potency
by weight refer to active ingredient weight
Indicators of antimicrobial use:
・AUD (antimicrobial use density): Mainly used to ascertain usage in medical institutions, AUD is calculated by
dividing the total titer of antimicrobials in a specified period by defined daily dose (DDD) as defined by the World

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