よむ、つかう、まなぶ。
【参考資料３】【英版R4.1.17】Nippon AMR One Health Report (NAOR) 2020 (55 ページ)
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Table 67. Resistance rates of Escherichia coli derived from healthy dogs and cats (%)
Agent
BP
＊
ABPC
32
CEZ
32＊
CEX
32†
CTX
4＊
MEPM
4＊
SM
32†
GM
16＊
KM
64＊
TC
16＊
CP
32＊
CL
4＊
NA
32＊
CPFX
1＊
76/4＊
ST
Strains tested (n)
Animal
Dogs
Cats
Dogs
Cats
Dogs
Cats
Dogs
Cats
Dogs
Cats
Dogs
Cats
Dogs
Cats
Dogs
Cats
Dogs
Cats
Dogs
Cats
Dogs
Cats
Dogs
Cats
Dogs
Cats
Dogs
Cats
Dogs
Cats
2018
33.8
28.5
19.2
17.1
17.9
18.4
13.2
10.8
0.0
0.0
19.2
11.4
3.3
2.5
5.3
1.9
16.6
10.8
4.6
1.3
0.0
0.0
27.8
24.7
18.5
12.0
13.2
12.0
151
158
2019
23.3
27.1
11.4
13.3
11.4
13.3
8.8
6.4
0.0
0.0
13.0
11.7
2.6
4.3
3.6
3.2
13.0
10.1
5.7
3.7
0.0
0.0
20.7
28.7
8.8
13.3
7.8
9.6
193
188
The unit of BP is μg/mL.
＊
BP follows CLSI Criteria.
＊
BP follows EUCAST Criteria.
ⅱ. Enterococcus spp.
The most common Enterococcus spp. in both dogs and cats were E. faecalis. E. faecium, E. gallinarum, E.
durans, E. hirae, E. avium, E. casseliflavus, and E. raffinosus were also collected. In strains isolated from dogs
and cats in both 2018 and 2019, the highest rate of resistance was to TC, followed by EM, while rates of resistance
to the other antimicrobials were less than 20%. The rates of resistance to critically important antimicrobial for
human medicine CPFX in dog- and cat-derived strains were 5.7-14.4%, while no VCM-resistant strains were
isolated.
Table 68. Resistance rates of Enterococcus spp. derived from healthy dogs and cats (%)
Agent*
BP
†
ABPC
16
GM
32§
TC
16†
CP
32†
EM
8†
CPFX
4†
VCM
32†
Strains tested (n)
Animal
Dogs
Cats
Dogs
Cats
Dogs
Cats
Dogs
Cats
Dogs
Cats
Dogs
Cats
Dogs
Cats
Dogs
Cats
2018
6.9
2.2
12.4
11.1
55.9
48.9
15.9
11.1
32.4
34.4
13.8
14.4
0.0
0.0
145
90
2019
1.9
3.4
7.0
15.7
41.8
61.8
10.1
14.6
23.4
34.8
5.7
13.5
0.0
0.0
158
89
The unit of BP is μg/mL.
AZM was also included in the scope of monitoring, the proportion of AZM-resistant strains were not listed because BP could not be
established.
†
BP follows CLSI Criteria.
* While
54
Agent
BP
＊
ABPC
32
CEZ
32＊
CEX
32†
CTX
4＊
MEPM
4＊
SM
32†
GM
16＊
KM
64＊
TC
16＊
CP
32＊
CL
4＊
NA
32＊
CPFX
1＊
76/4＊
ST
Strains tested (n)
Animal
Dogs
Cats
Dogs
Cats
Dogs
Cats
Dogs
Cats
Dogs
Cats
Dogs
Cats
Dogs
Cats
Dogs
Cats
Dogs
Cats
Dogs
Cats
Dogs
Cats
Dogs
Cats
Dogs
Cats
Dogs
Cats
Dogs
Cats
2018
33.8
28.5
19.2
17.1
17.9
18.4
13.2
10.8
0.0
0.0
19.2
11.4
3.3
2.5
5.3
1.9
16.6
10.8
4.6
1.3
0.0
0.0
27.8
24.7
18.5
12.0
13.2
12.0
151
158
2019
23.3
27.1
11.4
13.3
11.4
13.3
8.8
6.4
0.0
0.0
13.0
11.7
2.6
4.3
3.6
3.2
13.0
10.1
5.7
3.7
0.0
0.0
20.7
28.7
8.8
13.3
7.8
9.6
193
188
The unit of BP is μg/mL.
＊
BP follows CLSI Criteria.
＊
BP follows EUCAST Criteria.
ⅱ. Enterococcus spp.
The most common Enterococcus spp. in both dogs and cats were E. faecalis. E. faecium, E. gallinarum, E.
durans, E. hirae, E. avium, E. casseliflavus, and E. raffinosus were also collected. In strains isolated from dogs
and cats in both 2018 and 2019, the highest rate of resistance was to TC, followed by EM, while rates of resistance
to the other antimicrobials were less than 20%. The rates of resistance to critically important antimicrobial for
human medicine CPFX in dog- and cat-derived strains were 5.7-14.4%, while no VCM-resistant strains were
isolated.
Table 68. Resistance rates of Enterococcus spp. derived from healthy dogs and cats (%)
Agent*
BP
†
ABPC
16
GM
32§
TC
16†
CP
32†
EM
8†
CPFX
4†
VCM
32†
Strains tested (n)
Animal
Dogs
Cats
Dogs
Cats
Dogs
Cats
Dogs
Cats
Dogs
Cats
Dogs
Cats
Dogs
Cats
Dogs
Cats
2018
6.9
2.2
12.4
11.1
55.9
48.9
15.9
11.1
32.4
34.4
13.8
14.4
0.0
0.0
145
90
2019
1.9
3.4
7.0
15.7
41.8
61.8
10.1
14.6
23.4
34.8
5.7
13.5
0.0
0.0
158
89
The unit of BP is μg/mL.
AZM was also included in the scope of monitoring, the proportion of AZM-resistant strains were not listed because BP could not be
established.
†
BP follows CLSI Criteria.
* While
54