よむ、つかう、まなぶ。
【参考資料3】【英版R4.1.17】Nippon AMR One Health Report (NAOR) 2020 (63 ページ)
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出典情報 | 国際的に脅威となる感染症対策関係閣僚会議 薬剤耐性ワンヘルス動向調査検討会(第9回 1/17)《厚生労働省》 |
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Table 70. Trends in oral antimicrobial use in Japan based on the volume of sales
2013
Tetracyclines
Amphenicols
Penicillins with extended spectrum
Beta Lactamase-sensitive penicillins
Combinations of penicillins, including
beta lactamase inhibitors
1st generation cephalosporins
2nd generation cephalosporins
3rd generation cephalosporins
Carbapenems
Other cephalosporins and penems
Combinations of sulfonamides and
trimethoprim, including derivatives
Macrolides
Lincosamides
2014
2015
2016
2017
2018
2019
0.76
<0.01
0.88
<0.01
0.75
<0.01
0.89
<0.01
0.77
<0.01
0.99
<0.01
0.80
<0.01
0.97
<0.01
0.81
<0.01
0.95
<0.01
0.88
<0.01
1.01
<0.01
0.96
<0.01
1.13
<0.01
0.21
0.22
0.24
0.25
0.26
0.29
0.33
0.07
0.30
3.53
0.01
0.14
0.07
0.29
3.41
0.02
0.14
0.07
0.29
3.46
0.02
0.13
0.07
0.29
3.32
0.02
0.12
0.07
0.28
3.08
0.01
0.12
0.08
0.28
2.83
0.01
0.11
0.09
0.30
2.63
0.01
0.10
0.25
0.27
0.29
0.31
0.33
0.36
0.38
4.83
0.01
4.50
0.01
4.59
0.02
4.56
0.01
4.18
0.02
3.96
0.02
3.84
0.02
Fluoroquinolones
2.82
2.83
2.71
2.75
2.57
2.34
2.32
Other quinolones
0.01
<0.01
<0.01
<0.01
<0.01
<0.01
<0.01
0.10
13.57
0.09
12.76
0.08
12.25
0.08
12.19
Other antibacterials
0.10
0.10
0.10
Total
13.93
13.50
13.67
* As a unit, defined daily doses (DDDs) per 1,000 inhabitants per day (DID) is used.
* Figures for DDD are those for January 1, 2019.
Table 71. Trends in parenteral antimicrobial use in Japan based on the volume of sales
Tetracyclines
2013
0.02
2014
0.02
2015
0.02
2016
0.02
2017
0.02
2018
0.02
2019
0.02
Amphenicols
<0.01
<0.01
<0.01
<0.01
<0.01
< 0.01
< 0.01
0.04
0.04
0.04
0.04
0.04
0.05
0.05
Beta Lactamase-sensitive penicillins
Combinations of penicillins, including
beta lactamase inhibitors
1st generation cephalosporins
2nd generation cephalosporins
3rd generation cephalosporins
4th generation cephalosporins
<0.01
<0.01
<0.01
<0.01
<0.01
<0.01
0.01
0.13
0.15
0.16
0.18
0.19
0.21
0.22
0.13
0.11
0.18
0.06
0.13
0.11
0.19
0.05
0.14
0.10
0.21
0.05
0.14
0.10
0.22
0.05
0.15
0.10
0.23
0.05
0.15
0.09
0.24
0.04
0.12
0.10
0.27
0.04
Monobactams
<0.01
<0.01
<0.01
<0.01
<0.01
<0.01
<0.01
0.11
0.11
0.11
0.11
0.11
0.11
0.11
<0.01
<0.01
<0.01
<0.01
<0.01
<0.01
<0.01
<0.01
<0.01
<0.01
<0.01
<0.01
<0.01
<0.01
0.02
0.02
0.02
0.02
0.02
0.02
0.02
Streptogramins
<0.01
<0.01
<0.01
<0.01
<0.01
<0.01
<0.01
Streptomycin
<0.01
<0.01
<0.01
<0.01
<0.01
<0.01
<0.01
0.05
0.04
0.03
0.05
0.04
0.03
0.05
0.04
0.03
0.04
0.04
0.03
0.04
0.04
0.03
0.04
0.04
0.03
0.03
0.03
0.03
Polymyxins
<0.01
<0.01
<0.01
<0.01
<0.01
<0.01
<0.01
Metronidazole
<0.01
<0.01
<0.01
<0.01
<0.01
<0.01
<0.01
0.02
0.96
0.02
0.96
0.02
1.00
0.02
1.03
0.02
1.05
0.02
1.06
0.02
1.09
Penicillins with extended spectrum
Carbapenems
Combinations of sulfonamides and
trimethoprim, including derivatives
Macrolides
Lincosamides
Other aminoglycosides
Fluoroquinolones
Glycopeptides
Other antibacterials
Total
* As a unit, defined daily doses (DDDs) per 1,000 inhabitants per day (DID) is used.
* Figures for DDD are those for January 1, 2019.
62
2013
Tetracyclines
Amphenicols
Penicillins with extended spectrum
Beta Lactamase-sensitive penicillins
Combinations of penicillins, including
beta lactamase inhibitors
1st generation cephalosporins
2nd generation cephalosporins
3rd generation cephalosporins
Carbapenems
Other cephalosporins and penems
Combinations of sulfonamides and
trimethoprim, including derivatives
Macrolides
Lincosamides
2014
2015
2016
2017
2018
2019
0.76
<0.01
0.88
<0.01
0.75
<0.01
0.89
<0.01
0.77
<0.01
0.99
<0.01
0.80
<0.01
0.97
<0.01
0.81
<0.01
0.95
<0.01
0.88
<0.01
1.01
<0.01
0.96
<0.01
1.13
<0.01
0.21
0.22
0.24
0.25
0.26
0.29
0.33
0.07
0.30
3.53
0.01
0.14
0.07
0.29
3.41
0.02
0.14
0.07
0.29
3.46
0.02
0.13
0.07
0.29
3.32
0.02
0.12
0.07
0.28
3.08
0.01
0.12
0.08
0.28
2.83
0.01
0.11
0.09
0.30
2.63
0.01
0.10
0.25
0.27
0.29
0.31
0.33
0.36
0.38
4.83
0.01
4.50
0.01
4.59
0.02
4.56
0.01
4.18
0.02
3.96
0.02
3.84
0.02
Fluoroquinolones
2.82
2.83
2.71
2.75
2.57
2.34
2.32
Other quinolones
0.01
<0.01
<0.01
<0.01
<0.01
<0.01
<0.01
0.10
13.57
0.09
12.76
0.08
12.25
0.08
12.19
Other antibacterials
0.10
0.10
0.10
Total
13.93
13.50
13.67
* As a unit, defined daily doses (DDDs) per 1,000 inhabitants per day (DID) is used.
* Figures for DDD are those for January 1, 2019.
Table 71. Trends in parenteral antimicrobial use in Japan based on the volume of sales
Tetracyclines
2013
0.02
2014
0.02
2015
0.02
2016
0.02
2017
0.02
2018
0.02
2019
0.02
Amphenicols
<0.01
<0.01
<0.01
<0.01
<0.01
< 0.01
< 0.01
0.04
0.04
0.04
0.04
0.04
0.05
0.05
Beta Lactamase-sensitive penicillins
Combinations of penicillins, including
beta lactamase inhibitors
1st generation cephalosporins
2nd generation cephalosporins
3rd generation cephalosporins
4th generation cephalosporins
<0.01
<0.01
<0.01
<0.01
<0.01
<0.01
0.01
0.13
0.15
0.16
0.18
0.19
0.21
0.22
0.13
0.11
0.18
0.06
0.13
0.11
0.19
0.05
0.14
0.10
0.21
0.05
0.14
0.10
0.22
0.05
0.15
0.10
0.23
0.05
0.15
0.09
0.24
0.04
0.12
0.10
0.27
0.04
Monobactams
<0.01
<0.01
<0.01
<0.01
<0.01
<0.01
<0.01
0.11
0.11
0.11
0.11
0.11
0.11
0.11
<0.01
<0.01
<0.01
<0.01
<0.01
<0.01
<0.01
<0.01
<0.01
<0.01
<0.01
<0.01
<0.01
<0.01
0.02
0.02
0.02
0.02
0.02
0.02
0.02
Streptogramins
<0.01
<0.01
<0.01
<0.01
<0.01
<0.01
<0.01
Streptomycin
<0.01
<0.01
<0.01
<0.01
<0.01
<0.01
<0.01
0.05
0.04
0.03
0.05
0.04
0.03
0.05
0.04
0.03
0.04
0.04
0.03
0.04
0.04
0.03
0.04
0.04
0.03
0.03
0.03
0.03
Polymyxins
<0.01
<0.01
<0.01
<0.01
<0.01
<0.01
<0.01
Metronidazole
<0.01
<0.01
<0.01
<0.01
<0.01
<0.01
<0.01
0.02
0.96
0.02
0.96
0.02
1.00
0.02
1.03
0.02
1.05
0.02
1.06
0.02
1.09
Penicillins with extended spectrum
Carbapenems
Combinations of sulfonamides and
trimethoprim, including derivatives
Macrolides
Lincosamides
Other aminoglycosides
Fluoroquinolones
Glycopeptides
Other antibacterials
Total
* As a unit, defined daily doses (DDDs) per 1,000 inhabitants per day (DID) is used.
* Figures for DDD are those for January 1, 2019.
62