<) OLDO

血液感染について (米国)

REGULATORY UPDATE: AABB'S TTD
COMMITTEE MONITORING MONKEYPOX
OUTBREAK

Agy 23. 2022

AABB's Transfusion Transmitted Diseases (TTD) Committee is continuously monitoring developments related to
an ongoing outbreak of monkeypox following confirmation of a domestic case in Massachusetts and clusters of
international cases in Australia, Canada and several European countries.

According to CDC, cases of monkeypox have previously been identified in travelers from, or residents of, West
African or Central African countries where monkeypox is considered to be endemic: however, most of the recent
Cases do not have direct travel-associated exDOSure riSKs.

CDC emphasized that the risk to the public is low, but encouraged any individual who develops a new,
unexplained shin rash (with or without fever) to seek medical care immediately and avoid contact with others.If
possible, potentially exposed individuals should call ahead before going to a health care facility.

AABB reminds members that monkeypox is not known to be transfusion-transmissible, and there have been no
reports of transfusion-transmitted cases. AABB's TTD committee is updating AABB's Monkeypox Virus Fact
Sheet with relevant information.

AABB members may contact regulatory(@⑳aabb_-org with questions.
/ Currently Recommended Donor Deferral Period:
* 。 NoFDA Guidance or AABB Standard exists.

untiil signs and symptoms are gone Or a minimum of
21 days after the onset of symptoms.

* Based on the incubation period, CDC has recom-
mended that asymptomatic close contacts of infected
people or animals be placed under fever surveillance
for 21 days. The 21 days would be a minimum deferral

\、 if such contact has occurred.
* Prudent practice would be to defer donors at least Transmission by Blood Transfusion:

* Nocases have been documented.

へ
415 /