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参考資料１-１_長時間労働医師への健康確保措置に関するマニュアル（改訂版） (46 ページ)
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45. Taheri S, Lin L, Austin D, Young T, Mignot E. Short sleep duration is associated with
reduced leptin, elevated ghrelin, and increased body mass index. PLoS Med 2004;1:e62
46. Vgontzas AN, Chrousos GP. Sleep, the hypothalamic-pituitary-adrenal axis, and cytokines:
multiple interactions and disturbances in sleep disorders. Endocrinol Metab Clin North Am
2002;31:15–36
47. Akashiba T, Inoue Y, Uchimura N, Ohi M, Kasai T, Kawana F, Sakurai S, Takegami M, Tachikawa
R, Tanigawa T, Chiba S, Chin K, Tsuiki S, Tonogi M, Nakamura H, Nakayama T, Narui K, Yagi
T, Yamauchi M, Yamashiro Y, Yoshida M, Oga T, Tomita Y, Hamada S, Murase K, Mori H, Wada
H, Uchiyama M, Ogawa H, Sato K, Nakata S, Mishima K, Momomura SI. Sleep Apnea Syndrome
(SAS) Clinical Practice Guidelines 2020. Respir Investig. 2022 ;60(1):3-32.
48. Benjafield AV, Ayas NT, Eastwood PR, Heinzer R, Ip MSM, Morrell MJ, Nunez CM, Patel SR,
Penzel T, Pépin JL, Peppard PE, Sinha S, Tufik S, Valentine K, Malhotra A. Estimation of
the global prevalence and burden of obstructive sleep apnoea: a literature-based analysis.
Lancet Respir Med. 2019 ;7:687-698.
49. Rajesh S, Wonderling D, Simonds AK; Guideline Committee. Obstructive sleep apnoea/hypopnoea
syndrome and obesity hyperventilation syndrome in over 16s: summary of NICE guidance. BMJ.
2021 8;375:n2360.
50. 谷川武, 淡野桜子. 眠気のない睡眠時無呼吸(NOSSA)が及ぼす社会影響への取り組み, 日本医事新報
2010;4513:51-55
51. de Silva S, Abeyratne UR, Hukins C. Impact of gender on snore-based obstructive sleep apnea
screening. Physiol Meas 2012;33:587-601
52. Davies RJ, Crosby J, Prothero A, Stradling JR. Ambulatory blood pressure and left
ventricular hypertrophy in subjects with untreated obstructive sleep apnoea and snoring,
compared with matched control subjects, and their response to treatment. Clin Sci (Lond)
1994;86:417-424
53. Akashiba T, Kurashina K, Minemura H, Yamamoto H, Horie T. Daytime hypertension and the
effects of short-term nasal continuous positive airway pressure treatment in obstructive
sleep apnea syndrome. Am J Respir Intern Med 1995;34:528-532
54. Faccenda JF, Mackay TW, Boon NA, Douglas NJ. Randomized placebo-controlled trial of
continuous positive airway pressure on blood pressure in the sleep apnea-hypopnea syndrome.
Am J Respir Crit Care Med 2001;163:344-348 71
55. Marin JM, Carrizo SJ, Vicente E, Agusti AG. Long-term cardiovascular outcomes in men with
obstructive sleep apnoea-hypopnoea with or without treatment with continuous positive
airway pressure: an observational study. Lancet 2005;365:1046-1053
56. Tuomilehto H, Seppä J, Uusitupa M, Peltonen M, Martikainen T, Sahlman J, Kokkarinen J,
Randell J, Pukkila M, Vanninen E, Tuomilehto J, Gylling H, Kuopio Sleep Apnea Group. The
impact of weight reduction in the prevention of the progression of obstructive sleep apnea:
an explanatory analysis of a 5-year observational follow-up trial. Sleep Med 2014;15:329-
41
reduced leptin, elevated ghrelin, and increased body mass index. PLoS Med 2004;1:e62
46. Vgontzas AN, Chrousos GP. Sleep, the hypothalamic-pituitary-adrenal axis, and cytokines:
multiple interactions and disturbances in sleep disorders. Endocrinol Metab Clin North Am
2002;31:15–36
47. Akashiba T, Inoue Y, Uchimura N, Ohi M, Kasai T, Kawana F, Sakurai S, Takegami M, Tachikawa
R, Tanigawa T, Chiba S, Chin K, Tsuiki S, Tonogi M, Nakamura H, Nakayama T, Narui K, Yagi
T, Yamauchi M, Yamashiro Y, Yoshida M, Oga T, Tomita Y, Hamada S, Murase K, Mori H, Wada
H, Uchiyama M, Ogawa H, Sato K, Nakata S, Mishima K, Momomura SI. Sleep Apnea Syndrome
(SAS) Clinical Practice Guidelines 2020. Respir Investig. 2022 ;60(1):3-32.
48. Benjafield AV, Ayas NT, Eastwood PR, Heinzer R, Ip MSM, Morrell MJ, Nunez CM, Patel SR,
Penzel T, Pépin JL, Peppard PE, Sinha S, Tufik S, Valentine K, Malhotra A. Estimation of
the global prevalence and burden of obstructive sleep apnoea: a literature-based analysis.
Lancet Respir Med. 2019 ;7:687-698.
49. Rajesh S, Wonderling D, Simonds AK; Guideline Committee. Obstructive sleep apnoea/hypopnoea
syndrome and obesity hyperventilation syndrome in over 16s: summary of NICE guidance. BMJ.
2021 8;375:n2360.
50. 谷川武, 淡野桜子. 眠気のない睡眠時無呼吸(NOSSA)が及ぼす社会影響への取り組み, 日本医事新報
2010;4513:51-55
51. de Silva S, Abeyratne UR, Hukins C. Impact of gender on snore-based obstructive sleep apnea
screening. Physiol Meas 2012;33:587-601
52. Davies RJ, Crosby J, Prothero A, Stradling JR. Ambulatory blood pressure and left
ventricular hypertrophy in subjects with untreated obstructive sleep apnoea and snoring,
compared with matched control subjects, and their response to treatment. Clin Sci (Lond)
1994;86:417-424
53. Akashiba T, Kurashina K, Minemura H, Yamamoto H, Horie T. Daytime hypertension and the
effects of short-term nasal continuous positive airway pressure treatment in obstructive
sleep apnea syndrome. Am J Respir Intern Med 1995;34:528-532
54. Faccenda JF, Mackay TW, Boon NA, Douglas NJ. Randomized placebo-controlled trial of
continuous positive airway pressure on blood pressure in the sleep apnea-hypopnea syndrome.
Am J Respir Crit Care Med 2001;163:344-348 71
55. Marin JM, Carrizo SJ, Vicente E, Agusti AG. Long-term cardiovascular outcomes in men with
obstructive sleep apnoea-hypopnoea with or without treatment with continuous positive
airway pressure: an observational study. Lancet 2005;365:1046-1053
56. Tuomilehto H, Seppä J, Uusitupa M, Peltonen M, Martikainen T, Sahlman J, Kokkarinen J,
Randell J, Pukkila M, Vanninen E, Tuomilehto J, Gylling H, Kuopio Sleep Apnea Group. The
impact of weight reduction in the prevention of the progression of obstructive sleep apnea:
an explanatory analysis of a 5-year observational follow-up trial. Sleep Med 2014;15:329-
41