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「日本人の食事摂取基準（2025年版）」策定検討会報告書 (238 ページ)
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their related nutrients (United States). Cancer Causes Control. 1997;8(4):575-590.
59) Ishihara J, Otani T, Inoue M, et al. Low intake of vitamin B-6 is associated with increased risk of colorectal
cancer in Japanese men. J Nutr. 2007;137(7):1808-1814.
60) Institute of Medicine. The B Vitamins and Choline: Overview and Methods. In: Dietary Reference Intakes
for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline.
National Academies Press, Washington, D.C.; 1998:306-356.
61) Watanabe F. Vitamin B12 sources and bioavailability. Exp Biol Med (Maywood). 2007;232(10):1266-1274.
62) 渡辺文雄. ビタミン B12 の基礎. Modern Physician. 2007;27:1213-5．.
63) Darby WJ, Bridgforth EB, Le Brocquy J, et al. Vitamin B12 requirement of adult man. Am J Med.
1958;25(5):726-732.
64) Reizenstein P, Ek G, Matthews CM. Vitamin B12 kinetics in man. Implications on total-body-B12determinations, human requirements, and normal and pathological cellular B12 uptake. Phys Med Biol.
1966;11(2):295-306.
65) Adams JF, Tankel HI, MacEwan F. Estimation of the total body vitamin B12 in the live subject. Clin Sci.
1970;39(1):107-113.
66) Amin S, Spinks T, Ranicar A, et al. Long-term clearance of [57Co]cyanocobalamin in vegans and pernicious
anaemia. Clin Sci (Lond). 1980;58(1):101-103.
67) Boddy K, Adams JF. The long-term relationship between serum vitamin B12 and total body vitamin B12. Am
J Clin Nutr. 1972;25(4):395-400.
68) Bozian RC, Ferguson JL, Heyssel RM, et al. Evidence concerning the human requirement for vitamin B12:
Use of the whole body counter for determination of absorption of vitamin B12. Am J Clin Nutr. 1963;12:117129.
69) Watanabe F, Yabuta Y, Bito T, et al. Vitamin B12-containing plant food sources for vegetarians. Nutrients.
2014;6(5):1861-1873.
70) Bito T, Teng F, Watanabe F. Bioactive compounds of edible purple laver Porphyra sp. (Nori). J Agric Food
Chem. 2017;65(49):10685-10692.
71) Bor MV, von Castel-Roberts KM, Kauwell GP, et al. Daily intake of 4 to 7 μg dietary vitamin B-12 is
associated with steady concentrations of vitamin B-12-related biomarkers in a healthy young population.
Am J Clin Nutr. 2010;91(3):571-577.
72) 渡邉文雄. ビタミン B12 と葉酸の摂取量についての一考察. ビタミン. 2017;91(10):595-602.
73) Fenech M. Recommended dietary allowances (RDAs) for genomic stability. Mutat Res. 2001;480-481:5154.
74) 平岡真美, 安田和人. 女子大学生のビタミン B12、葉酸栄養状態について―血清ビタミン B12、葉酸
濃度の分布範囲―. ビタミン. 2000;74(5–6):271-280.
75) EFSA Panel on Dietetic Products, Nutrition, and Allergies (NDA). Scientific Opinion on Dietary Reference
Values for cobalamin (vitamin B12). EFSA J. 2015;13(7):4150.
76) Fernandes-Costa F, van Tonder S, Metz J. A sex difference in serum cobalamin and transcobalamin levels.
Am J Clin Nutr. 1985;41(4):784-786.
77) Shibata K, Fukuwatari T, Ohta M, et al. Values of water-soluble vitamins in blood and urine of Japanese
young men and women consuming a semi-purified diet based on the Japanese Dietary Reference Intakes. J
228
59) Ishihara J, Otani T, Inoue M, et al. Low intake of vitamin B-6 is associated with increased risk of colorectal
cancer in Japanese men. J Nutr. 2007;137(7):1808-1814.
60) Institute of Medicine. The B Vitamins and Choline: Overview and Methods. In: Dietary Reference Intakes
for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline.
National Academies Press, Washington, D.C.; 1998:306-356.
61) Watanabe F. Vitamin B12 sources and bioavailability. Exp Biol Med (Maywood). 2007;232(10):1266-1274.
62) 渡辺文雄. ビタミン B12 の基礎. Modern Physician. 2007;27:1213-5．.
63) Darby WJ, Bridgforth EB, Le Brocquy J, et al. Vitamin B12 requirement of adult man. Am J Med.
1958;25(5):726-732.
64) Reizenstein P, Ek G, Matthews CM. Vitamin B12 kinetics in man. Implications on total-body-B12determinations, human requirements, and normal and pathological cellular B12 uptake. Phys Med Biol.
1966;11(2):295-306.
65) Adams JF, Tankel HI, MacEwan F. Estimation of the total body vitamin B12 in the live subject. Clin Sci.
1970;39(1):107-113.
66) Amin S, Spinks T, Ranicar A, et al. Long-term clearance of [57Co]cyanocobalamin in vegans and pernicious
anaemia. Clin Sci (Lond). 1980;58(1):101-103.
67) Boddy K, Adams JF. The long-term relationship between serum vitamin B12 and total body vitamin B12. Am
J Clin Nutr. 1972;25(4):395-400.
68) Bozian RC, Ferguson JL, Heyssel RM, et al. Evidence concerning the human requirement for vitamin B12:
Use of the whole body counter for determination of absorption of vitamin B12. Am J Clin Nutr. 1963;12:117129.
69) Watanabe F, Yabuta Y, Bito T, et al. Vitamin B12-containing plant food sources for vegetarians. Nutrients.
2014;6(5):1861-1873.
70) Bito T, Teng F, Watanabe F. Bioactive compounds of edible purple laver Porphyra sp. (Nori). J Agric Food
Chem. 2017;65(49):10685-10692.
71) Bor MV, von Castel-Roberts KM, Kauwell GP, et al. Daily intake of 4 to 7 μg dietary vitamin B-12 is
associated with steady concentrations of vitamin B-12-related biomarkers in a healthy young population.
Am J Clin Nutr. 2010;91(3):571-577.
72) 渡邉文雄. ビタミン B12 と葉酸の摂取量についての一考察. ビタミン. 2017;91(10):595-602.
73) Fenech M. Recommended dietary allowances (RDAs) for genomic stability. Mutat Res. 2001;480-481:5154.
74) 平岡真美, 安田和人. 女子大学生のビタミン B12、葉酸栄養状態について―血清ビタミン B12、葉酸
濃度の分布範囲―. ビタミン. 2000;74(5–6):271-280.
75) EFSA Panel on Dietetic Products, Nutrition, and Allergies (NDA). Scientific Opinion on Dietary Reference
Values for cobalamin (vitamin B12). EFSA J. 2015;13(7):4150.
76) Fernandes-Costa F, van Tonder S, Metz J. A sex difference in serum cobalamin and transcobalamin levels.
Am J Clin Nutr. 1985;41(4):784-786.
77) Shibata K, Fukuwatari T, Ohta M, et al. Values of water-soluble vitamins in blood and urine of Japanese
young men and women consuming a semi-purified diet based on the Japanese Dietary Reference Intakes. J
228